The long-term thermal stability of structural alloys is critical to the safe and reliable operation of nuclear reactors. Laser powder bed fusion (LPBF) is a type of additive manufacturing that fuses thin layers of metal powders into net-shape components. However, unlike conventional wrought stainless-steel components that have a long track record of thermal stability, knowledge about thermally induced changes in LPBF components is sparse. A research team used the APS to address this knowledge gap.

In work that could be a leap forward for fibrosis treatment, a team has developed an antibody that can inhibit the progression of fibrosis by inhibiting leptin signaling. 

A team of scientists has used the Advanced Photon Source to determine the structure of a large protein complex. Their findings can potentially serve as the basis for drug design against vitamin B₁₂ deficiency.

An international team of scientists exploited interference effects in X-rays scattered from a quantum material and accurately reconstructed its quantum entanglement spectrum. They used a technique called resonant inelastic X-ray scattering to accomplish this.

RAS proteins function as on/off switches in pathways controlling cell growth and proliferation. Mutated RASs keep the pathways permanently activated, leading to conditions such as cancer and Noonan syndrome. Scientists have revealed how mutations in a particular protein disrupt RAS binding. Their findings support development of a molecular glue that could promote reduction of cancer-causing proteins.