14-ID-B beamline is an insertion device beamline with two U21 in-line undulators. A series of choppers, shutters and mirrors is used to isolate single ~250 ps X-ray pulses or longer pulse trains and to focus the X-ray beam onto the sample. In the standard mode of operation polychromatic beam is used and secondary KB mirrors permit focusing down to 25 x 15 µm^2 (H x V). This station supports Laue Time-Resolved Crystallography and Time-Resolved Solution Scattering. Special capabilities - Crystallography: single-crystal and serial time-resolved crystallography; reaction initiation methods: photo-initiation including caged compounds, temperature jump, mix-and-inject, electric-field-jump. Special capabilities - Solution scattering: time-resolved solution scattering with simultaneous SAXS and WAXS; reaction initiation methods: photo-initiation including caged compounds, temperature jump, pH jump.