19-BM is a Structural Biology Center (SBC) Legacy Beamline. SBC's mission is to advance and promote scientific and technological innovation in support of national and DOE missions by providing a world-class research instrument, providing scientific knowledge and developing new and novel methods. At the SBC we: Explore new opportunities in structural biology, proteomics, and genomics research with a significant focus on medicine, infectious disease and, structural dynamics. Tackle the most challenging structural biology problems to advance scientific knowledge. Exploit advances in macromolecular x-ray crystallography. Provide an advanced data collection facility at the APS to the national user community and maintain a high-profile user program. Research biocatalysis, which is highly relevant to energy resources, health, a clean environment, and national security. Are a critical component of the DOE's integrated biosciences mission. Work closely with Argonne Leadership Computing Facility and the Globus community toward the future of data handling and processing. Contribute to the expansion of existing programs.