In work that could be a leap forward for fibrosis treatment, a team has developed an antibody that can inhibit the progression of fibrosis by inhibiting leptin signaling. 

A team of scientists has used the Advanced Photon Source to determine the structure of a large protein complex. Their findings can potentially serve as the basis for drug design against vitamin B₁₂ deficiency.

An international team of scientists exploited interference effects in X-rays scattered from a quantum material and accurately reconstructed its quantum entanglement spectrum. They used a technique called resonant inelastic X-ray scattering to accomplish this.

RAS proteins function as on/off switches in pathways controlling cell growth and proliferation. Mutated RASs keep the pathways permanently activated, leading to conditions such as cancer and Noonan syndrome. Scientists have revealed how mutations in a particular protein disrupt RAS binding. Their findings support development of a molecular glue that could promote reduction of cancer-causing proteins.

Scientists have developed a novel instrument that can capture the complete X-ray absorption spectrum of a material in a single snapshot, potentially reducing measurement times from minutes to milliseconds. This new tool could enable researchers to observe rapid chemical reactions and dynamic processes in materials with unprecedented time resolution.