The Advanced Photon Source
a U.S. Department of Energy Office of Science User Facility

Experiment Hazard Class 6 - Chemicals

Applicability
The hazard controls described herein apply to all experiments involving various types of hazardous chemicals.  Hazard controls (associated with other hazard classes) may also apply to experiments in this hazard class.
 
Experiment Category

Experiments involving previously reviewed hazard controls are, in general, low or medium risk experiments.  Work with highly toxic chemicals, flammable chemicals, larger quantities of materials, etc. may change the classification to high risk.

Experiments involving new equipment, processes, or materials, or modified hazard control schemes are high risk experiments.

 
Experiment Hazard Control Verification Statements

Engineered Controls

Flammables/Combustibles (6.4)

Particularly Hazardous Substance (6.1)

(Carcinogen, Reproductive Toxin, High Degree of Acute Toxicity)

Oxidizers (6.5)Corrosives (6.2)Alkali MetalsToxic (6.3)
Chemical fume hoodChemical fume hoodChemical fume hoodChemical fume hoodChemical fume hoodChemical fume hood
Store in flammable storage cabinetStore in designated, posted area or cabinetStore in secondary spill trayStore in acid cabinet and secondary spill trayStore in secondary spill tray in a dry and well-ventilated areaStore in secondary spill tray
Eyewash stationEyewash stationEyewash stationEyewash stationEyewash stationEyewash station
Safety showerSafety showerSafety showerSafety showerSafety showerSafety shower
Spill Kit (if allowed by SOP review)Spill Kit (if allowed by SOP review)Spill Kit (if allowed by SOP review)Spill Kit (if allowed by SOP review)

Spill Kit (if allowed by SOP review)

Class D extinguishing media or sand

Spill Kit (if allowed by SOP review)

Procedural Controls

Flammables/Combustibles (6.4)

Particularly Hazardous Substance (6.1)

(Carcinogen, Reproductive Toxin, High Degree of Acute Toxicity)

Oxidizers (6.5)Corrosives (6.2)Alkali MetalsToxic (6.3)
Keep away from ignition sources.SOP that specifies safe practices under normal and emergency conditionsDo not store near flammable/combustible materials or organic compoundsSOP that specifies safe practices under normal and emergency conditions may be requiredSOP that specifies safe practices under normal and emergency conditions may be requiredSOP that specifies safe practices under normal and emergency conditions may be required.

Equipment Inspections

Flammables/Combustibles (6.4)

Particularly Hazardous Substance (6.1)

(Carcinogen, Reproductive Toxin, High Degree of Acute Toxicity)

Oxidizers (6.5)Corrosives (6.2)Alkali MetalsToxic (6.3)
As determined by reviewAs determined by reviewAs determined by reviewAs determined by reviewAs determined by reviewAs determined by review


Safety Training

Flammables/Combustibles (6.4)

Particularly Hazardous Substance (6.1)

(Carcinogen, Reproductive Toxin, High Degree of Acute Toxicity)

Oxidizers (6.5)Corrosives (6.2)Alkali MetalsToxic (6.3)
As determined by reviewAs determined by reviewAs determined by reviewAs determined by reviewAs determined by reviewAs determined by review

Signs/Labeling

Flammables/Combustibles (6.4)

Particularly Hazardous Substance (6.1)

(Carcinogen, Reproductive Toxin, High Degree of Acute Toxicity)

Oxidizers (6.5)Corrosives (6.2)Alkali MetalsToxic (6.3)
Manufacturer label or GHS label or NFPA 704 labelManufacturer label or GHS label or NFPA 704 labelManufacturer label or GHS label or NFPA 704 labelManufacturer label or GHS label or NFPA 704 labelManufacturer label or GHS label or NFPA 704 labelManufacturer label or GHS label or NFPA 704 label
    Dangerous When Wet 
      


PPE

Flammables/Combustibles (6.4)

Particularly Hazardous Substance (6.1)

(Carcinogen, Reproductive Toxin, High Degree of Acute Toxicity)

Oxidizers (6.5)Corrosives (6.2)Alkali MetalsToxic (6.3)
Closed toe, slip-resistant shoesClosed toe, slip-resistant shoesClosed toe, slip-resistant shoesClosed toe, slip-resistant shoesClosed toe, slip-resistant shoesClosed toe, slip-resistant shoes
Chemical goggles or safety glasses with faceshield for benchtop or fume hood work Chemical goggles or safety glasses with faceshield for benchtop or fume hood workChemical goggles or safety glasses with faceshield for benchtop or fume hood workChemical goggles or safety glasses with faceshield for benchtop or fume hood workChemical goggles or safety glasses with faceshield for benchtop or fume hood workChemical goggles or safety glasses with faceshield for benchtop or fume hood work
Chemical resistant gloves (refer to SDS or contact APS Safety Representative)Chemical resistant gloves (refer to SDS or contact APS Safety Representative)Chemical resistant gloves (refer to SDS or contact APS Safety Representative)Chemical resistant gloves (refer to SDS or contact APS Safety Representative)Chemical resistant gloves (refer to SDS or contact APS Safety Representative)Chemical resistant gloves (refer to SDS or contact APS Safety Representative)
Flame-Resistant (FR) laboratory coat may be required as determined by reviewButtoned laboratory coat Buttoned laboratory coat Buttoned laboratory coat
 No exposed hands and arms No exposed hands and arms No exposed hands and arms

NOTE: The need for use of PPE extends to the setup/maintenance/trouble shooting/disassembly of equipment that contained or may have contained hazardous materials.

View the Glove Selection Chart and Glove Type by Chemical

Chemical Monitoring

Flammables/Combustibles (6.4)

Particularly Hazardous Substance (6.1)

(Carcinogen, Reproductive Toxin, High Degree of Acute Toxicity)

Oxidizers (6.5)Corrosives (6.2)Alkali MetalsToxic (6.3)
As determined by review and consultation with Industrial HygieneAs determined by review and consultation with Industrial HygieneAs determined by review and consultation with Industrial HygieneAs determined by review and consultation with Industrial HygieneAs determined by review and consultation with Industrial HygieneAs determined by review and consultation with Industrial Hygiene
 
Hazardous Waste
If your work at the APS will generate hazardous chemical waste, you must work with your host Beamline to ensure hazardous chemical waste is stored and disposed of properly.   NOTE: Except in certain cases, waste chemicals and chemicals in general may not be disposed of down laboratory, restroom, or storm drains.
 
Experiment Authorization
Unless otherwise noted in the approved experiment safety plan, the PSC Deputy Associate Laboratory Director of Operations delegates the authority to authorize an experiment in this hazard class to a member of the APS Experiment Safety Review Board and resident beamline personnel having the authority to authorize experiments as listed in the ESAF system.  Approval by both the host beamline and APS Experiment Safety Review Board are mandatory prerequisites for experiment authorization.
 
Hazard Control Verification
The PSC Deputy Associate Laboratory Director of Operations delegates responsibility for verifying that required controls are in place to the experiment On-Site Spokesperson and Beamline Management.
 
References

LMS-PROC-354: Chemical Hygiene Plan 10/22/2021 (Internal link)

LMS-PROC-312: Chemical Safety Life Cycle 5/09/2023 (Internal link)

LMS-PROC-288: Hazard Communication for Chemicals 12/15/2023 (Internal link)

LMS-PROC-341: Evaluating Chemical and Chemical Process Risk in Research 03/04/2022 (Internal link)

Chemical Eye and Face Protection Guide 6/22/2015 (Internal link)

Contact the APS User Safety Program with any questions or if the internal links are not working properly.

Reviewed: February 22, 2024