Experimental Physics and
Industrial Control System

"I am trying to get a feel for how possible it would be to create a framework for this concept"
Qt5+ is certainly something you should have a look at.

https://www.qtdeveloperdays.com/north-america/track/17/web

QML (Qt Markup Language) GUIs can be served by a web-server
QtWebKit allows you to have hybrid applications (i.e. change the DOM with widgets)
QtWebChannel allows desktop applications to interact with others processes like a web browser
Qt has an extremely good and simple integration with (TCP-based) websockets.
QtWebEngine ...

Let me stop just here and say that HTML5 is one of the 3 officially supported GUI by the Qt framework.

But to tell you exactly what to use, I need to know
* where are the clients located (on your EPICS LAN?)
* what desired update rate and latency are,  (TCP or UDP?)
* what technology is used on the server side (stuck on webserver?)
* what the desired access rights are, (read only?)
etc.

Enjoy,

--
Emmanuel Mayssat
http://www.epicsqt.org