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Workshop 1—APS Life Science Future Directions

May 8, 2013 (all day)
Bldg. 402, Rm. Auditorium

Organizers: Keith Moffat (U. of Chicago), Robert Fischetti (Argonne National Laboratory),
Keith Brister (Northwestern U.)
, and B.C. Wang (University of Georgia)

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The APS life sciences community has a unique opportunity to leverage the advances planned by the APS-U to push forward on the next generation of life sciences experiments. This workshop will gather the community together to flesh out our plans for the next 5 to 10 years. The will enable us to present a coherent, APS-wide plan for beamline upgrades that will drive new science. The workshop will review the work we've accomplished so far as part of the original APS-U planning process, look at opportunities that have arisen since, and lay out a plan to achieve our goals.


8:30 Keith Moffat (Senior Advisor for Life Sciences at the APS)
Only Connect: Can Aspects of Our User Science Be Done Better Together? (abstract)
8:50 Gwyndaf Evans (Diamond Light Source)
Progress with In Situ Room-temperature Data Collection at Diamond Light Source (abstract)
9:20 Vadim Cherezov (The Scripps Research Institute)
Microcrystallography of G Protein-coupled Receptors (abstract)
9:50 Michael Malkowski (State University of New York at Buffalo)
Monotopic Membrane Enzymes: Structural Features Governing Catalysis at the Membrane Interface
10:20 Break
10:45 Osman Bilsel (University of Massachusetts Medical School)
Continuous Flow Microsecond SAXS (abstract)
11:15 Tobin R. Sosnick (University of Chicago)
SAXS/WAXS Studies of Proteins and RNAs: What Have We Done and What Do We Want? (abstract)
11:45 Duncan Kilburn (Johns Hopkins University)
RNA Folding in Crowded Solutions by SAXS
12:15 Lunch
1:40 Robert A. Scott (University of Georgia)
Metals in Biology: A Spectroscopist's View of High-energy-resolution Crystallography (abstract)
2:10 Bi-Cheng (B.C.) Wang (University of Georgia)
A New Tool for Biology and Crystallography: Exploring Biophysical/Biochemical Information of Metals and Other Atoms Using Wavelength-dependent Diffraction Data (abstract)
2:40 Vukica Srajer (University of Chicago/BioCARS)
Studies of Biological Macromolecules in Action: Current State and Challenges (abstract)
3:00 Break
3:30 James Penner-Hahn (University of Michigan)
Inorganic Physiology:  Interconnected Metal Homeostasis Patterns in Yeast (abstract)
4:00 Thomas V. O'Halloran (Northwestern University)
Inorganic Signals:  Quantitative Subcellular Mapping of Metal Fluxes in Mammalian Development and Disease (abstract)
4:30 Andrzej Joachimiak (Argonne National Laboratory)
Advanced Protein Crystallization Facility
4:45 Round Table Discussion
5:25 Summary
5:30 Adjourn

Updated 05/28/13