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2005
2004

Workshop 6

Metals and Metalloids in Cell Biology

Thursday, May 5, 2005
Location: Bldg. 402, Room E1100/E1200

Organizers:  Gayle Woloschak, Northwestern University, and Dina Mandoli, University of Washington

Recent studies in proteomics have lead to the identification of the "metaloproteome," the identification and study of metal-binding proteins. As this area of biology is exploding with new information, the application of the new data to intracellular studies is still lagging behind. This workshop will explore applications of x-ray microscopy to detection of metals/metal-binding proteins in cells. A special emphasis will be placed on new applications and novel approaches to using x-ray microscopy for studies in mammalian, bacterial, plant, and environmental systems.

2:00 pm

Hard X-ray Fluorescence Microscopy: Capabilities, Challenges, and Opportunities
Stefan Vogt, Advanced Photon Source

2:15

Analytical Electron and Other Microscopies
Peter Ingram, Duke University

2:45

Cell Growth and Electrolyte Homeostasis
Kouichi Iwasaki, Northwestern University

3:15

TiO2-DNA Nanocomposites in Mammalian Cells
Gayle Woloschak, Northwestern University

3:45

Break

4:00

Organellar Metal Ion Transporters for Zinc Storage, Detoxification, and Utilization
David Eide, University of Wisconsin, Madison

4:30

Arsenic Cell Biology and Physiology in a Giant Algal Model
Dina Mandoli, University of Washington, Seattle

5:00

Using X-ray Absorption Spectroscopy to Probe Metallocluster Biosynthesis in the Nitrogenase Enzyme System
Mary C. Corbett, Stanford University

5:30

Measuring Element Stoichiometries of Ocean Plankton with a Hard X-ray Fluorescence Microprobe
Benjamin Twining, SUNY at  Stonybrook

6:00 Adjourn

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