Advanced Photon Source User Activity Report

Biological Science

A unique zinc-binding site revealed by the high-resolution x-ray structure of homotrimeric Apo2L/TRAIL
S.G. Hymowitz, M.P. O'Connell, M.H. Ultsch, A. Hurst, K. Totpal, A. Ashkenazi, R.F. Kelley, and A.M. de Vos

b-carbonic anhydrase active site architecture is a mirror image of a-carbonic anhydrases
E.F. Pai and M.S. Kimber

Binding of Cd ions to the cell wall of B. Subtilis - an EXAFS study
M. Boyanov, D. Fowle, K. Kemner, B. Bunker, and J. Fein

Crystallographic evidence for Try157 functioning as the active site base in human UDP-galactose 4-epimerase
J.B. Thoden, T.M. Wohlers, J.L. Fridovich-Keil, and H.M. Holden

Crystallographic studies of dsDNA phage HK97 structure and maturation
W.R. Wikoff, Z. Che, W. Schildkamp, L. Liljas, R.L. Duda, R.W. Hendrix, and J.E. Johnson

Crystallographic studies of Thermus aquaticus RNA polymerase
S.A. Darst, E.A. Campbell, and K. Murakami

Crystallographic studies of Thermus aquaticus RNA polymerase
S.A. Darst, G. Zhang, E.A. Campbell, and C. Richter

Crystallographic studies on the ribosome, a large macromolecular assembly exhibiting severe nonisomorphism, extreme beam sensitivity, and no internal symmetry
A. Yonath, J. Harms, H.A. Hansen, A. Bashan, F. Schlunzen, I. Levin, I. Kolln, A. Tocilj, I. Agmon, M. Peretz, H. Bartels, W.S. Bennett, S. Krumbholz, D. Janell, S. Weinstein, T. Auerbach, H. Avila, M. Piolleti, S. Morlang, and F. Franceschi

Crystallography of ribosomes
A. Yonath

Crystal structure of Bacillus subtilisYabJ, a purine regulatory protein and member of the highly conserved YjgF family
J.L. Smith, S. Sinha, P. Rappu, S.C. Lange, P. Mantsala, and H. Zalkin

Crystal structure of bovine milk xanthine dehydrogenase and its conversion to the oxidase form by proteolytic cleavage
E.F. Pai, C. Enroth, B.T. Eger, K. Okamoto, T. Nishino, and T. Nishino

Crystal structure of human glutathione synthetase
M.W. Parker, G. Polekhina, J. Rossjohn, P.G. Board, and R.R. Gali

Crystal structure of isocitrate dehydrogenase from Bacillus subtilis
S.K. Singh, S.P. Miller, D.C. LaPorte, and L.J. Banaszak

Crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana
S. Suresh, S. Turley, F.R. Opperdoes, P.A.M. Michels, and W.G.J. Hol

Crystal structure of nicotinamide mononucleotide adenylyltransferase from Methanobacterium thermoautotrophicum with bound NAD+
V. Saridakis, D. Christendat, M. Kimber, A.M. Edwards, and E.F. Pai

Crystal structure of the catalytic portion of human HMG-CoA reductase
E.S. Istvan, M. Palnitkar, S.K. Buchanan, and J. Deisenhofer

Crystal structure of the E. coliYrdC protein
M. Egli, M. Teplova, V. Tereshko, R. Sanishvili, A. Joachimiak, and W.E. Anderson

Crystal structure of the electron transfer flavoprotein, ubiquinone oxidoreductase
J. Zhang, R. Paschke, F.E. Frerman, and J.-J.P. Kim

Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus
DNA polymerase I: structural basis for nucleotide incorporation
Y. Li, S. Korolev, and G. Waksman

Data collection and structure determination of Pariacoto virus
L. Tang, K. Johnson, A. Ball, T. Lin, and J.E. Johnson

Direct evidence of structural changes affecting electron transfer rate from QA to QB in photosynthetic bacterial reaction center proteins probed by Fe2+ binding site using XAFS
L. Chen, L. Utschig, P. Laible, S. Schlesselman, D. Hanson, and D. Tiede

Electrostatic stress in catalysis:  structure and mechanism of the enzyme orotidine monophosphate decarboxlyase
E.F. Pai, N. Wu, Y. Mo, and J. Gao

Elucidating the medium-resolution structure of ribosomal particles:  an interplay between electron cryomicroscopy and x-ray crystallography
A. Yonath, J. Harms, A. Tocilj, I. Levin, I. Agmon, H. Stark, I. Kolln, M. van Heel, M. Cuff, F. Schlunzen, A. Bashan, and F. Franceschi

Functional universality and evolutionary diversity:  insights from the structure of the ribosome
A. Yonath and F. Franceschi

In vivox-ray diffraction of indirect flight muscle from Drosophila melanogaster
T.C. Irving and D.W. Maughan

Iron and lead sequestration at the soil-root interface
C. Hansel, S. Fendorf, S. Sutton, and M. Newville

Lambda-6 light chain, Wil
P.R. Pokkuluri, A. Solomon, D.T. Weiss, F.J. Stevens, and M. Schiffer

P.R. Pokkuluri, M. Szpunar, F.J. Stevens, and M. Schiffer

P.R. Pokkuluri, X. Cai, F.J. Stevens, and M. Schiffer

P.R. Pokkuluri, X. Cai, M. Gu, F.J. Stevens, and M. Schiffer

P.R. Pokkuluri, R. Raffen, L. Dieckman, C. Boogard, F.J. Stevens, and M. Schiffer

P.R. Pokkuluri, X. Cai, F.J. Stevens, and M. Schiffer

P.R. Pokkuluri, X. Cai, G. Johnson, F.J. Stevens, and M. Schiffer

P.R. Pokkuluri, R. Raffen, F.J. Stevens, and M. Schiffer

MAD phasing on the SBC-CAT 19-ID undulator beamline at the APS
R. Sanishvili, G. Evans, M. Walsh, R. Zhang, R. Alkire, and A. Joachimiak

Mechanism of hyaluronan binding and degradation: structure of Streptococcus pneumoniae hyaluronate lyase in complex with hyaluronic acid disaccharide at 1.7 Å resolution
K. Ponnuraj and M.J. Jedrzejas

Metal compounds as tools for the construction and the interpretation of medium-resolution maps of ribosomal particles
A. Yonath, S. Weinstein, W. Jahn, C. Glotz, F. Schlunzen, I. Levin, D. Janell, J. Harms, I. Kolln, H.A. Hansen, M. Gluhmann, W.S. Bennett, H. Bartels, A. Bashan, I. Agmon, M. Kessler, M. Pioletti, H. Avila, K. Anagnostopoulos, M. Peretz, T. Auerbach, and F. Franceschi

Microdiffraction of DNA-membrane self-assemblies for gene delivery applications
G. Wong, Y. Li, I. Koltover, C. Safinya, Z. Cai, and W. Yun

Monomeric sarcosine oxidase: structure of a covalently flavinylated amine oxidizing enzyme
P. Trickey, M. Wagner, M.S. Jorns, and F.S. Mathews

N10-formyltetrahydrofolate synthetase
R. Radfar, W. Minor, and L. Lebioda

Nuclear inelastic scattering of synchrotron radiation on metmyoglobin
K. Achterhold, C. Keppler, U. van Burck, W. Potzel, W. Sturhahn, E.E. Alp, and F. Parak

Probing covalent flavinylation in the flavocytochrome p-cresol methylhydroxylase
L.M. Cunane, Z.-W. Chen, F.S. Mathews, and W.S. McIntire

Rapid protein crystal structure determination using third-generation synchrotron sources
M.A. Walsh, I. Dementieva, G. Evans, R. Sanishvili, and A. Joachimiak

Sexual attraction in the silkworm moth: structure of the pheromone-binding protein-bombykol complex
B.H. Sandler, L. Nikonova, W.S. Leal, and J. Clardy

P.R. Pokkuluri, R. Raffen, F.J. Stevens, and M. Schiffer

Small-angle x-ray scattering from concentrated ternary mixtures of eye lens crystallins
G. Thurston, L. Lurio, S. Mochrie, O. Ogun, J. Pande, and G. Benedek

Small-angle x-ray scattering studies of tertiary folding of tRNAphe
X. Fang, K. Littrell, X-j. Yang, S. Henderson, S. Seifert, P. Thiyagarajan, T. Pan, and T.R. Sosnick

Structural and function changes in photosynthetic bacterial reaction center proteins induced by incorporating different metal ions
L. Chen, L. Utschig, P. Laible, S. Schlesselman, D. Hanson, and D. Tiede

Structural determinants for visual arrestin's specificity and basal state
C. Schubert, P.B. Sigler, and J.A. Hirsch

Structural determinants of preinitiation complex assembly on human Pol II promoters
F.T.F. Tsai and P.B. Sigler

Structural studies of a functional form of pneumolysin: a virulence factor from Streptococcus pneumoniae
S. Kelly and M.J. Jedrzejas

Structural studies of an ecotin variant
G. Pal, H. Christinger, A.A. Kossiakoff, and C. Wiesmann

Structural studies of a soluble monomeric quinohemoprotein alcohol dehydrogenases from Pseudomonas putida HK5
F.S. Mathews, Z.-w. Chen, K. Matsushita, T. Yamashita, H. Toyama, O. Adachi, and H.D. Bellamy

Structural studies of FceRI
C. Eigenbrot and J. Stamos

Structural studies of p185/HER2
F.F. Vajdos, H. Christinger, and A.M. de Vos

Structural studies of the recombinant flavin-binding domain of bakers yeast flavocytochrome b2
L.M. Cunane, J.D. Barton, Z.-w. Chen, F.S. Mathews, F.E. Welsh, S.K. Chapman, and G.A. Reid

Structure and recognition of sheared tandem G x A base pairs associated with human centromere DNA sequence at atomic resolution
Y.G. Gao, H. Robinson, R. Sanishvili, A. Joachimiak, and A.H. Wang

Structure determination of Ascaris pepsin inhibitor-3 by MAD phasing
K.K.S. Ng, J.F.W. Peterson, M.M. Cherney, C. Garen, M.N.G. James, J.L. Zalatoris, C. Rao-Naik, B.M. Dunn, M.R. Martzen, and R.J. Peanasky

Structure determination of Streptomyces plicatusb-N-acetylhexosaminidase by MAD phasing
B.L. Mark, B.L. Triggs-Raine, and M. James

Structure of a manganese-containing homoprotocatechuate 2,3-dioxygenase from Arthrobacter globiformus CM-2 at 1.5 Å resolution
M. Vetting and D. Ohlendorf

Structure of homoprotocatechuate 2,3-dioxygenase from Brevibacterium fuscum at 1.6 Å resolution
M. Vetting and D. Ohlendorf

Structure of streptococcal pyrogenic exotoxin A
C. Earhart, G. Vath, M. Roggiani, P. Schlievert, and D. Ohlendorf

Structure studies of g-carboxymuconolactone decarboxylase from Acinetobacter sp. ADP1
M. Vetting and D. Ohlendorf

Submillisecond time-resolved small-angle x-ray scattering from b-lactoglobulin
L. Pollack, M. Tate, G. Toombes, A. Finnefrock, S. Gruner, C. Kalidas, S. Trotter, C. Batt, N. Darnton, R. Austin, L. Lurio, and S. Mochrie

Succinyl-CoA synthetase and succinyl-CoA:3-oxoacid CoA transferase
M.E. Fraser and W.T. Wolodko

The small ribosomal subunit from Thermus thermophilusat 4.5 Å resolution:  pattern fittings and the identification of a functional site
A. Yonath, A. Tocilj, F. Schlunzen, D. Janell, M. Gluhmann, H.A. Hansen, J. Harms, A. Bashan, H. Bartels, I. Agmon, and F. Franceschi

The small subunit of carbamoyl phosphate synthetase:  snapshots along the reaction pathway
J.B. Thoden, X. Huang, F.M. Raushel, and H.M. Holden

The structural basis for the oriented assembly of a TBP/TFB/promoter complex
O. Littlefield, Y. Korkhin, and P. Sigler

The Structural Biology Center at the Advanced Photon Source
G. Rosenbaum, R. Alkire, N.C. Duke, S.L. Ginell, F. Rotella, R. Sanishvilli, R. Zhang, and A. Joachimiak

The structure of the ligand-binding domain of neurexin 1b: regulation of LNS domain function by alternative splicing
G. Rudenko, T. Nguyen, Y. Chelliah, T.C. Sudhof, and J. Deisenhofer

The three-dimensional molecular packing structure of collagen
J. Orgel, T. Wess, A. Miller, T. Irving, and A. Hammersly

The three-dimensional structure of Escherichia coliasparagine synthetase B:  a short journey from substrate to product
T.M. Larsen, S.K. Boehlein, S.M. Schuster, N.G.J. Richards, J.B. Thoden, H.M. Holden, and I. Rayment

Thymidylate synthase
J. Phan, W. Minor, and L. Lebioda

Time-efficient data collection on crystals of the large ribosomal subunit from Haloarcula marimortui
P. Nissen, N. Ban, J. Hansen, P.B. Moore, and T.A. Steitz

Ultrahigh-resolution diffraction from the 'blue' copper protein anicyanin
C.J. Carrell, Z.-W. Chen, L.M. Cunane, P. Trickey, and F.S. Mathews

Un- and refolding kinetics of WT staphylococcal nuclease
J. Woenckhaus, R. Köhling, C.A. Royer, P. Thiyagarajan, K. Littrell, S. Seifert, and R. Winter

Using Q-XAS to determine zinc speciation in a contaminated environment
S. Webb and J. Gaillard

Viral and human membrane glycoproteins
D. Wiley

X-ray absorption studies on the early development of Xenopus laevis (frog) oocytes
K. Zhang and D. Auld

X-ray crystallography of bovine rhodopsin
T. Okada, I. Le Trong, C.A. Behnke, B.A. Fox, D.C. Teller, R.E. Stenkamp, and K. Palczewski

X-ray crystal structure of peptide-bound GroEL
L. Chen and P.B. Sigler

X-ray diffraction studies of cardiac muscle
T.C. Irving, J. Konhilas, D. Perry, R. Fischetti, and P.P. deTombe

X-ray diffraction studies of the molecular substructure of human articular cartilage
M. Aurich, J. Mollenhauer, and T.C. Irving

X-ray fiber diffraction of the indirect flight muscle of Lethocerus indicus
M.K. Reedy, J.W. Squire, B. Baunann, A. Stewart, R. Fischetti, and T. Irving

X-ray imaging and microscopy of plants and fungi
W. Yun, S.T. Pratt, R.M. Miller, Z. Cai, D.B. Hunter, A.G. Jarstfer, K.M. Kemner, B. Lai, H.-R. Lee, D.G. Legnini, W. Rodrigues, and C.I. Smith

X-ray studies of recombinant rat kidney long-chain hydroxy acid oxidase
L.M. Cunane, J.D. Barton, Z.-w. Chen, F.S. Mathews, A. Belmouden, K.H.D. Lê, and F. Lederer