Science and Research Highlights

How Serotonin Receptors Can Shape Drug Effects, from LSD to Migraine Medication

How Serotonin Receptors Can Shape Drug Effects, from LSD to Migraine Medication

May 15, 2013

New findings by researchers carrying out experiments at the U.S. Department of Energy Office of Science’s Advanced Photon Source help explain why some drugs that interact with two kinds of human serotonin receptors have had unexpectedly complex and sometimes harmful effects.
X-rays Paint a Picture of Picasso's Pigments

X-rays Paint a Picture of Picasso's Pigments

April 30, 2013

Art historians have long supposed that Pablo Picasso employed ordinary house paint, in place of conventional artists' paints, in some of his artwork. A recent collaborative effort between the Art Institute of Chicago and two Argonne National Laboratory research facilities utilized twenty-first century research to demonstrate conclusively that pigment from one of Pablo Picasso's paintings was indeed derived from a common house paint of the era in which he created the art work.
Antibody Evolution Could Guide HIV Vaccine Development

Antibody Evolution Could Guide HIV Vaccine Development

April 25, 2013

Observing the evolution of a particular type of antibody in an HIV-infected patient has provided insights that will enable vaccination strategies that mimic antibody development within the body, thanks to a multi-institution study carried out at the U.S. Department of Energy’s Los Alamos National Laboratory and Advanced Photon Source at Argonne National Laboratory
Blue Ruthenium Dimer Catalysis for Hydrogen Generation

Blue Ruthenium Dimer Catalysis for Hydrogen Generation

April 15, 2013

Scientists utilizing a variety of spectroscopic techniques to probe the catalysis process, including x-ray absorption spectroscopy at the U.S. Department of Energy Office of Science’s Advanced Photon Source, reported progress in revealing previously unknown mechanistic details about blue dimer’s water oxidation reaction, which may result in cost-effect, practical, and sustainable alternative energy sources.
A High-Pressure Nano-imaging Breakthrough

A High-Pressure Nano-imaging Breakthrough

April 11, 2013

A major breakthrough in measuring the structure of nanomaterials under extremely high pressures has been achieved by researchers carrying out experiments at the U.S. Department of Energy Office of Science’s Advanced Photon Source at Argonne National Laboratory. Their method for avoiding the distortions of high-energy x-ray beams utilized to image the structure of a gold nanocrystal could lead to new nanomaterials created under high pressures and a greater understanding of what happens in planetary interiors.
Protein Structure Could Lead to Better Treatments for HIV, Early Aging

Protein Structure Could Lead to Better Treatments for HIV, Early Aging

April 9, 2013

A breakthrough that could eventually help researchers develop new treatments for early-aging diseases and redesign AIDS medications to avoid side effects such as diabetes is the result of research was carried out at the U.S. Department of Energy Office of Science’s Advanced Photon Source at Argonne National Laboratory.
The Superpower behind Iron Oxyfluoride Battery Electrodes

The Superpower behind Iron Oxyfluoride Battery Electrodes

April 2, 2013

Electrodes based on “conversion chemistry” have the potential to double energy storage capacities compared to electrodes in existing lithium-ion batteries, but the electrochemical reactions giving rise to this improved performance remain a mystery. Scientists utilizing the U.S. Department of Energy Office of Science’s Advanced Photon Source at Argonne investigating the fundamental basis for the performance advantage gained new element-specific insights that represent significant milestones in understanding electrochemical reactions in battery electrodes and in the experimental tools available to investigate such reactions.
Shedding Light on Chemistry with a Biological Twist

Shedding Light on Chemistry with a Biological Twist

March 14, 2013

Discovering how living things absorb and convert light energy into a form that can change the molecules involved in such processes would not only help scientists understand them, but could lead to ways to mimic such processes for more efficient solar energy conversion, for instance. A clearer understanding of how light can drive biological processes has emerged from x-ray diffraction studies carried out on beamlines at the U.S. Department of Energy Office of Science’s Advanced Photon Source and the European Synchrotron Radiation Facility, helping shed a brighter light on some of life's most critical processes.
Watching a Protein as it Functions

Watching a Protein as it Functions

March 14, 2013

For decades, biochemists and biophysicists have worked to reveal the relationship between protein structural complexity and function, only to discover more complexity. They relied on freeze-trapping to capture protein intermediates at various steps along a biochemical pathway. Now a research group has developed the necessary infrastructure at the BioCARS beamline at the Argonne Advanced Photon Source to watch proteins function in real time on the picosecond time scale. Their work brings us many steps closer to knowing how proteins function, or malfunction when leading to disease.
Teasing Out the Nature of Structural Instabilities in Ceramic Compounds

Teasing Out the Nature of Structural Instabilities in Ceramic Compounds

March 12, 2013

Researchers utilized the U.S. Department of Energy Office of Science’s Advanced Photon Source at Argonne National Laboratory, as well as the European Synchrotron Radiation Facility, to study the rare-earth magnetic material europium titanate. In a magnetic field, the (near) optical properties of this material change quite dramatically, presenting hope of a strong magneto-electric material often dreamed of by engineers for use in combining magnetic and charge parameters for many memory, processing, and sensor devices.
Doubling Estimates of Light Elements in the Earth's Core

Doubling Estimates of Light Elements in the Earth's Core

March 1, 2013

Researchers utilizing Advanced Photon Source x-rays have developed a new model of how sound waves travel through iron and iron-silicon alloys. Their results suggest that the amount of light elements in the inner core of the Earth could be two times more than estimated in previous studies.
A New Material for Warm-White LEDs

A New Material for Warm-White LEDs

February 20, 2013

Light-emitting diodes (LEDs) are known for their energy efficiency and durability. But the bluish, cold light of current white LEDs has precluded their widespread use for indoor lighting. Now, with a critical assist from the U.S. Department of Energy Office of Science’s Advanced Photon Source, scientists have fabricated what is thought to be the world's first LED that emits a warm white light utilizing a single light-emitting material, or phosphor, with a single emitting center for illumination.
Probing Ultrafast Solvation Dynamics with High Repetition-Rate Laser/X-ray Methodologies

Probing Ultrafast Solvation Dynamics with High Repetition-Rate Laser/X-ray Methodologies

February 11, 2012

Thanks to implementation of a high-repetition-rate, high-power laser system at the U.S. Department of Energy Office of Science’s Advanced Photon Source at Argonne National Lsboratory, it has become possible to study light-induced intramolecular processes and solvent interactions in rapidly evolving molecular systems.
Ultrafast X-Ray Spectroscopy as a Probe of Nonequilibrium Dynamics in Ruthenium Complexes

Ultrafast X-Ray Spectroscopy as a Probe of Nonequilibrium Dynamics in Ruthenium Complexes

February 8, 2013

Researchers from Argonne National Laboratory and Northern Illinois University have shown that the ultrafast x-ray spectroscopy technique employed at a high-brightness x-ray light source such as the Argonne Advanced Photon Source can produce valuable new information about the physics underlying photoexcitation.
The Electronic Origin of Photoinduced Strain

The Electronic Origin of Photoinduced Strain

February 8, 2013

Research at the U.S. Department of Energy’s Advanced Photon Source and Center for Nanoscale Materials that adds to our understanding of the way light interacts with multiferroics represents an important step toward the development of future electronic devices.
Modifying Proteins to Combat Disease

Modifying Proteins to Combat Disease

January 22, 2013

Thanks to the efforts of a research team from Eli Lilly and Company, with the help of the Lilly Research Laboratories Collaborative Access Team x-ray beamline at the U.S. Department of Energy Office of Science’s Advanced Photon Source, the structure of an important methylation enzyme is now known. The results of this research can be utilized to provide new direction and focus in the race to create drugs to combat disease, especially cancer.
Higher Temperature at the Earth’s Core

Higher Temperature at the Earth’s Core

January 21, 2013

Exactly how hot is the center of the Earth? Apparently hotter than we had thought, according to new investigations by researchers working at the U.S. Department of Energy Office of Science’s Advanced Photon Source.
Clues about Rheumatoid Arthritis Damage

Clues about Rheumatoid Arthritis Damage

January 7, 2013

Utilizing high-brightness Advanced Photon Source x-rays, researchers with the Illinois Institute of Technology viewed the actions of an antibody targeted toward the proteoglycan biglycan — one of a group of polysaccharide-protein conjugates present in connective tissue and cartilage — that may help illustrate the underlying pathology of rheumatoid arthritis.