Workshop on Evolution and Control of Complexity:
Key Experiments Using Sources of Hard X-rays

Program: Focus Panel 4 - Controlling Biological Functions

Chair: Sol Gruner (Cornell)
Co-Chair: Ian McNulty (Argonne National Laboratory)

Oct 11, 2010, Monday, Room B3100
16:40 -17:10	Focus Panel Introductions and Statement of Goals
17:10 – 17:40	Chris Jacobsen, Argonne Nat'l Lab and Northwestern University *X-ray microscopy: freezing complex biological processes* (Bio, Abstract, Talk)
Oct 12, 2010, Tuesday, Room B3100
08:00 – 08:30	Coffee and Refreshments
Future Vision for Biology
08:30 – 09:00	Sol M. Gruner, Cornell University *Some Grand Challenges in Synthetic Biology* (Bio, Abstract, Talk)
09:00 – 09:30	Ilme Schlichting, Max Planck Institute for Medical Research, Heidelberg *FELs - emerging opportunities in structural biology* (Bio, Abstract, Talk)
09:30 – 10:00	John C.H. Spence, Arizona State University *Femtosecond nanodiffraction using a hard x-ray laser* (Bio, Abstract, Talk)
10:00 – 10:30	Recap, Discussions and Draft Summaries
10:30 – 11:00	Break
11:00 – 11:30	Marius Schmidt, University of Wisconsin, Milwaukee *Energetics of Biological Macromolecules from Five-Dimensional Crystallographic Data* (Bio, Abstract, Talk)
11:30 – 12:00	Peter Schwander , University of Wisconsin-Milwaukee Structure and its Variations from Random Low-Signal Snapshots (Bio, Abstract, Talk)
12:00 – 12:30	Recap, Discussions and Draft Summaries
12:30 – 14:00	Lunch
Protein Dynamics and Folding
14:00 – 14:30	Soichi Wakatsuki , Photon Factory, Structural Biology Research Center *Biological nanomachines and their control* (Bio, Abstract, Talk)
14:30 – 15:00	Sebastian Doniach, Stanford University *Use of correlated xray scattering (CXS) to track protein motions during enzyme catalysis by means of an xray freeelectron laser* (Bio, Abstract, Talk)
15:00 – 15:30	Andrew H. Marcus, University of Oregon, Eugene *Controlling Structure and Energy Transfer in Liposome Ordered Porphyrin Aggregates by Fluorescence-Detected 2D Electronic Spectroscopy* (Bio, Abstract, Talk)
15:30 – 16:00	Break
16:00 – 16:30	Karl F. Freed, University of Chicago *Protein Folding: Predicting Structure from Sequence* (Bio, Abstract, Talk)
16:30 – 17:00	A.C. McIntosh, ERRI, SPEME, University of Leeds *Suggestions for experimental work concerning the protein folding* (Bio, Abstract, Talk)
17:00 – 18:00	Recap, Discussions and Draft Summaries, Writing Assignments
18:00	No-host Dinner, Argonne Guest House
Oct 13, 2010, Wednesday, Room B3100
08:00 – 08:30	Coffee and Refreshments
Towards Organismal Biology
08:30 – 09:00	Lee Makowski, Northeastern University, Boston *Probing Protein Ensembles and Functional Intermediates with X-ray Solution Scattering* (Bio, Abstract, Talk)
09:00 – 09:30	Keith C. Cheng, Penn State Hershey College of Medicine, Hershey *Defining the Phenomic Landscape for Genes, Chemicals, and Diseases* (Bio, Abstract, Talk)
09:30 – 10:00	Focus Panels: Summary Preparation and Editing Assignments
10:00 – 10:30	Break
10:30 – 12:00	Focus Panels: Summary Presentation Preparation
12:00 – 13:30	Lunch
Oct 13, 2010, Wednesday, Plenary Session, 401 Auditorium
13:30 – 15:15	Summary Presentations from Focus Panels (15 minutes each)
15:15 – 15:30	Workshop Summary
15:30	Adjourn