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Chris Jacobsen

Associate Division Director/Senior Physicist

Photon Sciences

Argonne National Laboratory
9700 S. Cass Ave
Building 401-C4239

(630) 252-7960 • email


Chris Jacobsen is an Associate Division Director in the X-ray Science Division at the Advanced Photon Source at Argonne, where he works with the imaging, microscopy, optics, and detector groups.  He is also a Professor in the Department of Physics & Astronomy, Northwestern University, Evanston, Illinois,  and a member of the Graduate Program in Applied Physics and the Chemistry for Life Processes Institute at Northwestern.  He moved to Argonne and Northwestern in 2010 from a position as a Professor in the Department of Physics & Astronomy at Stony Brook University, Stony Brook, New York where he was on the faculty since 1991.

Selected Publications

  1. C. Holzner, M. Feser, S. Vogt, B. Hornberger, S.B. Baines, and C. Jacobsen, “Zernike phase contrast scanning microscopy with X-rays,” Nature Physics 6, 883-887 (2010)
  2. M.D. de Jonge, C. Holzner, S.B. Baines, B.S. Twining, K. Ignatyev, J. Diaz, D.L. Howard, D. Legnini, A. Miceli, I. McNulty, C.J. Jacobsen, and S. Vogt, “Quantitative 3D elemental microtomography of Cyclotella meneghiniana at 400-nm resolution,” Proceedings of the National Academy of Sciences 107, 15676-15680 (2010).
  3. J. Nelson, X. Huang, J. Steinbrener, D. Shapiro, J. Kirz, S. Marchesini, A.M. Neiman, J.J. Turner, and C. Jacobsen, “High resolution x-ray diffraction microscopy of specifically labeled yeast cells,” Proceedings of the National Academy of Sciences 107, 7235 (2010).
  4. J. Steinbrener, J. Nelson, X. Huang, S. Marchesini, D. Shapiro, J. J. Turner and C. Jacobsen, "Data preparation and evaluation techniques for x-ray diffraction microscopy", Optics Express 18, 18598-18614, (2010).
  5. X. Huang, J. Nelson, J. Kirz, E. Lima, S. Marchesini, H. Miao, A.M. Neiman, D. Shapiro, J. Steinbrener, A. Stewart, J.J. Turner, and C. Jacobsen, “Soft x-ray diffraction microscopy of a frozen hydrated yeast cell,” Physical Review Letters 103, 198101 (2009).
  6. M. Howells, T. Beetz, H. Chapman, C. Cui, J. Holton, C. Jacobsen, J. Kirz, E. Lima, S. Marchesini, H. Miao, D. Sayre, D. Shapiro, J. Spence, and D. Starodub, “An assessment of the resolution limitation due to radiation-damage in x-ray diffraction microscopy,” Journal of Electron Spectroscopy and Related Phenomena 170, 4–12 (2009).
  7. M. D. de Jonge, B. Hornberger, D. Paterson, C. Holzner, D. Legnini, I. McNulty, C. Jacobsen, and S. Vogt, “Quantitative phase imaging with a scanning transmission x-ray microscope,” Physical Review Letters 100, 163902 (2008).
  8. J. Lehmann, D. Solomon, J. Kinyangi, L. Dathe, S. Wirick, and C. Jacobsen, “Spatial complexity of soil organic matter forms at nanometre scales,” Nature Geoscience 1, 238-242 (2008).
  9. D. Shapiro, P. Thibault, T. Beetz, V. Elser, M. Howells, C. Jacobsen, J. Kirz, E. Lima, H. Miao, A. M. Neiman, and D. Sayre, “Biological imaging by soft x-ray diffraction microscopy,” Proceedings of the National Academy of Sciences 102, 15343-15346 (2005).
  10. C.K. Boyce, M.A. Zwieniecki, G.D. Cody, C. Jacobsen, S. Wirick, A.H. Knoll, and N. M. Holbrook, “Evolution of xylem lignification and hydrogel transport regulation.”  Proceedings of the National Academy of Sciences 101, 17555-17558 (2004).
  11. J. Kirz, C. Jacobsen, and M. Howells, “Soft x-ray microscopes and their biological applications.” Quarterly Reviews of Biophysics 28, 33-130 (1995).

Research Interests

My research interests involve developing new methods in x-ray imaging and applying them to problems in biology, environmental science, and materials science.


B.A. (Physics), St. Olaf College, Northfield, Minnesota, 1983.
Ph.D. (Physics), Stony Brook University, Stony Brook, New York, 1988.
Postdoc, Center for X-ray Optics, Lawrence Berkeley National Lab, 1988-1989.
Postdoc, Department of Physics, Stony Brook University, Stony Brook, New York, 1989-1990.

Awards and Honors

Presidential Faculty Fellow (White House/NSF), 1992-1997.
International Dennis Gabor Award (Hungary), 1996.
Kurt Heinrich Award (Microbeam Analysis Society), 2001.
Fellow, American Association for the Advancement of Science, 2001.
Fellow, Optical Society of America, 1999.
R&D 100 Award (cryoSTXM), 1999.
Most Outstanding Teacher Award, Department of Physics & Astronomy, Stony Brook University, 1996, 2002.

Additional Information

Web page: http://xrm.phys.northwestern.edu/~jacobsen/
Public calendar: http://xrm.phys.northwestern.edu/~jacobsen/#calendar